A marked police car has rolled "several times" after a Ford sedan crashed into it on a suburban street in Adelaide's south.
Police were travelling on Seaview Road in Victor Harbor just after 1.30am when the sedan crashed into it.
South Australia Police said both officers in the car received minor injuries, were treated at South Coast Hospital and had since been discharged.
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"The female driver of the Ford sustained serious, life-threatening injuries and was taken to the Flinders Medical Centre," police said in a statement.
The male passenger in the Ford was not injured.
Officers are asking residents to avoid the area.
"Seaview Road is currently closed between Hindmarsh Road and William Street. Acraman Street and Carlyle Street are also closed," police said this morning.
Major crash investigators are investigating.
