Prime Minister Scott Morrison has left The Lodge after two weeks' isolation ahead of today's National Cabinet meeting.
Mr Morrison was in quarantine following his trip to the UK for the G7.
Politicians are expected to discuss a deal on lockdowns, as a debate continues on when Australia could see an end to the stay-at-home orders.
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Ministers need to come to an agreement on a vaccine target which could end snap lockdowns and state border closures.
Tensions over the vaccine rollout are also expected to come to ahead in today's meeting.
Earlier this week Mr Morrison announced a major shakeup to the rollout, saying AstraZeneca could be administered to those under 40 with consultation from their GP.
This shakeup goes against ATAGI advice and was quickly refuted by Queensland state premier Annastacia Palaszczuk and Chief Health Officer Dr Jeanette Young who urged under 40s to stick to Pfizer.
Mr Morrison will also be under pressure to slash the number of international arrivals at today's National Cabinet meeting.
The Labor states want international arrivals slowed to a trickle to reduce the risk of bringing in the Delta variant of COVID-19.
There are about 34,000 Australians still trying to get home from overseas.Queensland, Victoria and WA want the 6000 people allowed into the nation each week to be cut.